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. 2020 Jun 1;17:20. doi: 10.1186/s12014-020-09281-y

Fig. 1.

Fig. 1

a Schematic diagram of proteomics experimental workflow. Synovial fluids of ankylosing spondylitis (AS), osteoarthritis (OA), gout, and rheumatoid arthritis (RA) were subject to immunodepletion using the multiple affinity removal system (MARS) and followed by trypsinization and LC–MS/MS analysis. MaxQuant LFQ (MaxLFQ) analysis was carried out for quantitative comparison. b Venn diagram showing the unique and shared protein groups and peptides identified in the synovial fluid of each group