Table 2.
The effects of berberine on serum hormones level in fructose-fed mice.
| Group | Dose (mg/kg) |
Orexin (pg/mL) |
Leptin (ng/mL) |
Adiponectin (ng/mL) |
Glucagon (ng/L) |
|---|---|---|---|---|---|
| Control | – | 15.69 ± 2.60 | 0.13 ± 0.03 | 2.68 ± 0.20 | 194.1 ± 7.44 |
| Fructose | – | 39.40 ± 5.05# | 0.28 ± 0.06# | 1.50 ± 0.08### | 245.6 ± 17.69 |
| Pioglitazone | 10 | 28.20 ± 2.77 | 0.29 ± 0.05 | 2.33 ± 0.14*** | 227.7 ± 9.27 |
| Berberine | 50 | 30.36 ± 3.61 | 0.16 ± 0.05* | 2.35 ± 0.09*** | 225.5 ± 21.43 |
| 100 | 23.45 ± 2.63* | 0.16 ± 0.02* | 2.46 ± 0.24*** | 206.9 ± 13.64 | |
| 200 | 20.18 ± 4.30* | 0.13 ± 0.03* | 2.80 ± 0.18*** | 197.1 ± 18.27 |
Data were expressed as mean ± S.E.M. n = 10. #p < 0.05, ###p < 0.001 vs control group; *p < 0.05, **p < 0.01, ***p < 0.001 vs fructose group.