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. Author manuscript; available in PMC: 2021 Jun 1.
Published in final edited form as: Breast Cancer Res Treat. 2020 Apr 13;181(2):309–322. doi: 10.1007/s10549-020-05630-5

Figure 4.

Figure 4

Association of lymphovascular invasion (LVI) with genomic alterations in primary tumors of TCGA-BRCA cohort. a Tukey boxplots of values for the LVI-positive and -negative cases are shown for various cancer genome characteristics. P values in two-group comparisons were calculated with standard t tests. CNA, copy number alteration; HRD, homologous recombinant defect; ITH, intra-tumor heterogeneity; SNV, single nucleotide variation. b The barplots show LVI incidence rates among tumors with and without mutations in five genes that are most frequently mutated in the cohort. Fisher’s exact test was used to determine the p values.