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eGFR after administration of 90 mg tin protoporphyrin
| Group | eGFR (ml/min per 1.73 m2) | ||
|---|---|---|---|
| Baseline | Day 2 Post-SnPP | Day 4 Post-SnPP | |
| Healthy volunteers | 84±6 | 87±5 | 88±4 |
| CKD3 | 46±6 | 50±6 | 47±6 |
| CKD4 | 20±4 | 23±5 | 22±4 |
The values are given are means±1 SD. There were no significant eGFR changes from baseline in response to the highest test dose of SnPP (90 mg). CKD3, stage 4 CKD (eGFR of 30–59 ml/min per 1.73 m2); CKD 4, stage 4 CKD (eGFR of 5–29 ml/min per 1.73 m2); SnPP, tin protoporphyrin.
