Table 4.
Associations of continuous eGFR with walking-while-talking gait domains derived using factor analysis
Gait Domain | eGFR≥60, per 10-ml/min per 1.73 m2 Lower eGFR, n=196 | eGFR<60, per 10-ml/min per 1.73 m2 Lower eGFR, n=134 | Age, per 5-yr Older Age, n=330 | |||
---|---|---|---|---|---|---|
Coefficient (95% CI) | P Value | Coefficient (95% CI) | P Value | Coefficient (95% CI) | P Value | |
Rhythm | 0.1 (−0.01 to 0.2) | 0.08 | −0.2 (−0.3 to −0.1) | <0.001 | −0.2 (−0.3 to −0.2) | <0.001 |
Pace | −0.04 (−0.2 to 0.1) | 0.50 | −0.01 (−0.1 to 0.1) | 0.84 | −0.1 (−0.2 to 0.02) | 0.12 |
Variability | 0.1 (−0.05 to 0.2) | 0.23 | −0.04 (−0.2 to 0.1) | 0.52 | 0.1 (−0.02 to 0.2) | 0.13 |
Multivariable linear regression adjusting for age, sex, race, education, body mass index, neuropathy, number of comorbidities, and number of medications was performed. Linear splines for eGFR were constructed with knot placed at 60 ml/min per 1.73 m2. 95% CI, 95% confidence interval.