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In vivo coronary vasodilator responses in control and FH swine. Percent increases in coronary vascular conductance (CVC) (i.e., coronary vasodilation) were assessed during infusion of (a) the endothelium-dependent vasodilator ATP, (b) the endothelium-independent nitric oxide donor sodium nitroprusside (SNP), and (c) the endothelium-independent ATP-sensitive potassium channel (KATP) opener bimakalim. Values are mean ± SE, *p<0.05 main effect FH versus control.
