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The fecal metabolome is distinct in participants with kidney stone disease. (A) PCA of untargeted fecal metabolite survey. (B) LDA distinguishes those with kidney stones from controls with 77% accuracy. (C) Metabolites increased (right) and decreased (left) in those who form kidney stones. (D) Correlation of metabolite concentration and bacterial abundance. Stars indicate significant correlations, after controlling for study group. PC, principal component.
