TABLE 1.
MIC distributions of Ureaplasma parvum, Ureaplasma urealyticum, and Mycoplasma hominis
| Antibiotic (MIC μg/ml)a | No. of isolates with an MIC (μg/ml) of: |
MIC (μg/ml) |
Resistance (n [%]) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 0.125 | 0.25 | 0.5 | 1 | 2 | 4 | 8 | 16 | 32 | >32 | 50% | 90% | ||
| U. parvum (418 strains) | |||||||||||||
| LVX (≥4) | 0 | 4 | 4 | 22 | 34 | 49 | 141 | 82 | 48 | 34 | 8 | 32 | 354 (84.69) |
| MXF (≥4) | 3 | 7 | 28 | 57 | 108 | 105 | 64 | 30 | 11 | 5 | 4 | 16 | 215 (51.44) |
| ERY (≥6) | 7 | 3 | 30 | 114 | 122 | 85 | 42 | 9 | 4 | 2 | 2 | 8 | 15 (3.59) |
| DOX | 200 | 88 | 80 | 37 | 6 | 4 | 1 | 1 | 0 | 1 | 0.25 | 1 | NAb |
| U. urealyticum (74 strains) | |||||||||||||
| LVX (≥4) | 0 | 0 | 1 | 1 | 11 | 11 | 22 | 16 | 10 | 2 | 8 | 32 | 61 (82.43) |
| MXF (≥4) | 0 | 2 | 2 | 14 | 10 | 19 | 20 | 5 | 2 | 0 | 4 | 8 | 46 (62.16) |
| ERY (≥16) | 1 | 0 | 1 | 5 | 24 | 25 | 14 | 4 | 0 | 0 | 4 | 8 | 4 (5.40) |
| DOX | 16 | 18 | 19 | 15 | 5 | 1 | 0 | 0 | 0 | 0 | 0.5 | 1 | NA |
| M. hominis (13 strains) | |||||||||||||
| LVX (≥2) | 0 | 0 | 1 | 1 | 0 | 2 | 2 | 1 | 6 | 0 | 16 | 32 | 11 (84.62) |
| MXF (≥0.5) | 2 | 0 | 2 | 1 | 1 | 1 | 2 | 4 | 0 | 0 | 4 | 16 | 11 (84.62) |
| CLI (≥0.5) | 8 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0.125 | 16 | 5 (38.46) |
| DOX | 10 | 0 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0.125 | 0.5 | NA |
a
LVX, levofloxacin; MXF, moxifloxacin; ERY, erythromycin; DOX, doxycycline; CLI, clindamycin.
b
NA, not applicable (no CLSI breakpoint).