TABLE 4.
MIC and FICI results with the combinations of MIN and azoles against Fusarium spp.
| Strain | MICa (μg/ml) for: |
||||||
|---|---|---|---|---|---|---|---|
| Agent alone |
Combinationb |
||||||
| MIN | ITC | VRC | POS | MIN/ITC | MIN/VRC | MIN/POS | |
| F. solani | |||||||
| FS1 | 32 | 32 | 2 | 16 | 4/8(S) | 8/0.5(S) | 16/4(I) |
| FS2 | 32 | 32 | 1 | 8 | 16/16(I) | 16/1(I) | 16/4(I) |
| FS3 | 32 | >64 | 2 | 16 | 8/16(S) | 8/0.5(S) | 8/2(S) |
| FS4 | 16 | >64 | 2 | 16 | 8/16(I) | 8/0.5(I) | 8/4(I) |
| FS5 | 16 | 32 | 2 | 16 | 16/16(I) | 8/1(I) | 8/8(I) |
| FS6 | 32 | 32 | 1 | 32 | 8/8(S) | 16/1(I) | 8/8(S) |
| FS7 | 32 | >64 | 4 | 16 | 8/8(S) | 8/1(S) | 8/4(S) |
| FS8 | 16 | 32 | 2 | 8 | 16/16(I) | 8/0.5(I) | 8/4(I) |
| FS9 | 32 | 32 | 4 | 8 | 8/8(S) | 8/1(S) | 8/2(S) |
| FS10 | 16 | 32 | 2 | 16 | 8/8(I) | 16/1(I) | 8/4(I) |
| F. oxysporum | |||||||
| FO1 | 16 | 32 | 2 | 8 | 8/16(I) | 8/2(I) | 8/8(I) |
| FO2 | 32 | 32 | 2 | 16 | 8/8(S) | 16/1(I) | 8/4(S) |
| FO3 | 32 | 32 | 4 | 8 | 16/16(I) | 8/1(S) | 8/2(S) |
a
The MIC is the concentration achieving 100% growth inhibition.
b
FICI results are shown in parentheses. S, synergy (FICI of ≤0.5); I, no interaction (indifference) (0.5 < FICI ≤ 4).