TABLE 5.
Details of the five patients infectious for A. minimus by DMFAs during the 28-day follow-upa
| Day or recrudescence, day | Patient identifier | Treatment | Sex | Age (yr) | Gametocytemia (no. of gametocytes/μl) | Gametocyte detection by TaqMan RT-PCR | Infection prevalence (proportion of infected females ± 95% CI) | Infection intensity (mean no. of oocysts ± SE) |
|---|---|---|---|---|---|---|---|---|
| 0 | D_002 | DP-SLDPQ | F | 29 | 562 | Positive | 41.7 ± 14 | 4.7 ± 0.97 |
| 1 | 336 | Positive | 0 | NA | ||||
| 2 | 48 | Positive | 0 | NA | ||||
| 3 | 0 | Positive | 0 | NA | ||||
| 7 | NA | Negative | 0 | NA | ||||
| 14 | NA | Negative | 0 | NA | ||||
| 21 | NA | Negative | 0 | NA | ||||
| 28 | 0 | Positive | 0 | NA | ||||
| Rec1, 0 (124)b | D_002 | QN-TE | 24 | Positive | 10 ± 8.3 | 2.6 ± 1.4 | ||
| Rec1, 3 (127) | 64 | Positive | 0 | NA | ||||
| Rec1, 7 (131) | 168 | Positive | 0 | NA | ||||
| 0 | N_015 | DP-SLDPQ | M | 23 | 787 | Positive | 16 ± 10 | 2.12 ± 0.4 |
| 1 | 2,208 | Positive | 0 | NA | ||||
| 2 | 40 | Positive | 0 | NA | ||||
| 3 | 176 | Positive | 0 | NA | ||||
| 7 | NA | Negative | 0 | NA | ||||
| 14 | NA | Negative | 0 | NA | ||||
| 28 | NA | Negative | 0 | NA | ||||
| Rec1, 0 (28) | N_035 | QN | F | 8 | 1,823 | Positive | 0 | NA |
| Rec1, 3 (31) | 11,912 | Positive | 0 | NA | ||||
| Rec1, 7 (35) | 7,904 | Positive | 94.3 ± 7.7 | 82.6 ± 5.5 | ||||
| 0 | N_046 | DP | M | 8 | 1,432 | Positive | 0 | NA |
| 2 | 2,904 | Positive | 0 | NA | ||||
| 3 | 3,952 | Positive | 0 | NA | ||||
| 7 | 1,952 | Positive | 0 | NA | ||||
| 14 | 432 | Positive | 6 ± 6.5 | 1 | ||||
| 28 | 16 | Positive | 0 | NA | ||||
| 0 | N_074 | DP-SLDPQ | M | 25 | 540 | Positive | 86.3 ± 9.4 | 11.3 ± 1.7 |
| 3 | 8 | Positive | 0 | NA |
a
QN-TE, quinine plus tetracycline; Rec1, the first recrudescence; CI, confidence interval; NA, data not available; F, female; M, male.
b
The day after initial infection is indicated in parentheses.