TABLE 2.
Predictor variables associated with treatment failure among intensive care unit patients receiving ceftriaxone
| Variablea | Treatment outcome: |
P value | |
|---|---|---|---|
| Success (n = 188) | Failure (n = 24) | ||
| Median SOFA score (IQR) | 3 (0–6) | 9 (7–12) | <0.0001 |
| No. mechanical ventilation (%) | 33 (17.6) | 11 (45.8) | 0.0029 |
| No. vasopressor support (%) | 30 (16.0) | 13 (54.2) | <0.0001 |
| Median creatinine clearance at 72 h (IQR) | 73.0 (46.4–106.0) | 54.8 (35.0–67.3) | 0.0121 |
a
SOFA, sequential organ failure assessment; IQR, interquartile range.