TABLE 1.
Demographic data, MLST, and antimicrobial susceptibility profile of optrA-positive E. faecalis isolates from swine in Brazila
| Isolate | State and farm | ST | optrAb | cfr | poxtA | 23S rRNA and L3/L4 mutations | MIC (μg/ml) for: |
||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| LZD | TZD | CHL | FFC | TGC | TET | DAP | TYL | STR | SYN | ERY | CIP | PEN | VAN | NIT | GEN | KAN | |||||||
| E. faecalis L10 | SP piggery B | 711 | P1 | − | − | WT | 8 | 1 | 128 | 128 | 0.12 | >32 | 2 | >32 | >2,048 | 16 | >8 | >4 | 2 | 2 | 8 | >1,024 | >1,024 |
| E. faecalis L11 | DF piggery B | 591 | P1 | + | − | WT | 8 | 1 | 128 | 128 | 0.12 | >32 | 2 | 4 | >2,048 | 16 | 0.5 | 2 | 2 | 1 | 32 | <128 | <128 |
| E. faecalis L12 | MG piggery A | 711 | P1 | − | − | WT | 8 | 1 | 128 | 128 | 0.25 | <1 | 2 | >32 | >2,048 | >32 | >8 | 1 | 4 | 2 | 16 | >1,024 | >1,024 |
| E. faecalis L13 | SC piggery A | 591 | P1 | − | − | WT | 8 | 1 | 64 | 128 | 0.25 | >32 | 1 | >32 | >2,048 | >32 | >8 | >4 | 16 | 2 | 16 | >1,024 | >1,024 |
| E. faecalis L15 | DF piggery A | 591 | P1 | + | − | WT | 8 | 1 | 128 | 128 | >0.5 | >32 | 4 | >32 | >2,048 | 8 | 4 | 2 | 4 | 2 | 16 | <128 | 256 |
| E. faecalis L16 | MT piggery A | 591 | P1 | − | − | WT | 16 | 1 | 128 | 128 | 0.12 | >32 | 2 | >32 | >2,048 | 16 | >8 | >4 | 4 | 1 | 16 | >1,024 | >1,024 |
| E. faecalis L18 | SC piggery A | 591 | P1 | − | − | WT | 8 | 1 | 128 | 128 | 0.25 | >32 | 2 | >32 | >2,048 | 16 | >8 | >4 | 2 | 2 | 16 | >1024 | >1,024 |
| E. faecalis L21 | PR piggery A | 591 | P1 | − | − | WT | 8 | 1 | 128 | 128 | 0.12 | >32 | 2 | >32 | >2,048 | 16 | >8 | >4 | 4 | 1 | 16 | >1,024 | >1,024 |
| E. faecalis L8 | SP piggery A | 710 | P2 | − | − | WT | 8 | 1 | 128 | 128 | 0.12 | >32 | 2 | >32 | >2,048 | 8 | 4 | 4 | 1 | 1 | 8 | >1,024 | >1,024 |
| E. faecalis L14 | PR piggery A | 330 | P3 | − | + | WT | 8 | 1 | 128 | 128 | 0.12 | >32 | 2 | >32 | >2,048 | 16 | >8 | >4 | 4 | 1 | 16 | >1,024 | >1,024 |
| E. faecalis L17 | PR piggery A | 330 | P3 | − | + | WT | 8 | 1 | 128 | 128 | 0.12 | >32 | 2 | >32 | >2,048 | 16 | >8 | >4 | 4 | 1 | 16 | >1,024 | >1,024 |
| E. faecalis L19 | PR piggery A | 330 | P3 | − | − | WT | 8 | 1 | 128 | 128 | 0.25 | >32 | 2 | >32 | >2,048 | 16 | 2 | >4 | 4 | 1 | 32 | >1,024 | >1,024 |
| E. faecalis L9 | DF piggery A | 29 | P4 | + | − | WT | 8 | 1 | 128 | 128 | >0.5 | >32 | 4 | >32 | >2,048 | 8 | 4 | 2 | 4 | 2 | 16 | <128 | 256 |
a
MLST, multilocus sequence typing; WT, wild-type; PR, Paraná; SC, Santa Catarina; DF, Distrito Federal; SP, São Paulo; MG, Minas Gerais; MT, Mato Grosso; LZD, linezolid; TZD, tedizolid; CHL, chloramphenicol; FFC, florfenicol; TGC, tigecycline; TET, tetracycline; DAP, daptomycin; TYL, tylosin; STR, streptomycin; SYN, quinupristin-dalfopristin; ERY, erythromycin; CIP, ciprofloxacin; PEN, penicillin; VAN, vancomycin; NIT, nitrofurantoin; GEN, gentamicin; KAN, kanamycin.
b
Genetic context of optrA.