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. 2020 May 21;64(6):e02026-19. doi: 10.1128/AAC.02026-19

FIG 5.

FIG 5

Changes in doubling dilution MIC independently associated with each feature/testing method (multivariable random-effects model). Purple represents testing using 2:1 CLSI-based agar dilution (CLSI), and green represents testing using EUCAST-based agar dilution. All elements except those denoted by an asterisk (*) and shaded in orange are modeled as binary presence versus absence effects (see the supplementary methods): other_bla (grouped other bla genes, includes blaTEM-40 [n = 2], blaTEM-30 [n = 3], blaCMY-2 [n = 3], blaOXA-48 [n = 1], blaTEM-190 [n = 1], blaTEM-33 [n = 1]; Table S2 in the supplemental material), blaOXA:2d (Bush-Jacoby 2d, blaOXA), blaCTXM:2be (Bush-Jacoby 2be, CTXM), blaTEM:2b (Bush-Jacoby 2b, blaTEM), blaSHV:2b, (Bush-Jacoby 2b, SHV), ampCpr (ampC promoter mutation suggesting increased expression), blaTEMpr (blaTEM hyperproducing promoter), NFOMP (nonfunctional ompF/ompC), blaTEM:2b:cpn (copy number) effect modeled as effect of doubling copy number, and blaSHV:2b:cpn (copy number) effect modeled as effect of doubling copy number.