TABLE 2.

Pharmacokinetic parameters of ibrexafungerp on day 7 after intravenous administration of 2.5, 5, 7.5, 10, and 15 mg/kg/day in infected rabbits

Dose of Ibrexafungerp (mg/kg)	AUC(0-24) (ng·hr/ml)	Cmax (ng/ml)	CL (liters/h)	V (liters)
2.5	50,384 ± 5,529	25,300 ± 1,700	0.12 ± 0.01	0.78 ± 0.17
5	98,548 ± 4,929	32,250 ± 4,307	0.13 ± 0.02	2.13 ± 0.63
7.5	137,421 ± 48,519	23,550 ± 3,761	0.19 ± 0.05	2.32 ± 0.23
10	162,869 ± 79,897	37,581 ± 9,962	0.35 ± 0.14	1.51 ± 0.28
15	260,041 ± 56,638	65,550 ± 8,689	0.18 ± 0.05	1.64 ± 0.23