Table 2.

Treatment-related adverse events in 32 patients

Treatment-related events	Any grade	Grade 1–2	Grade 3	Grade 4
Anemia	19 (59)	18 (56)	1 (3)	–
Neutropenia	26 (81)	19 (59)	6 (19)	1 (3)
Thrombocytopenia	20 (62)	2 (6)	7 (22)	11 (34)
Nausea	29 (91)	29 (91)	–	–
Vomit	4 (13)	4 (13)	–	–
Constipation	7 (22)	7 (22)
Fatigue	21 (66)	21 (66)	–	–
Rash	1 (3)	1 (3)	–	–
Fever	11 (34)	11 (34)	–	–
Elevated alanine aminotransferase	9 (28)	8 (25)	1 (3)	–
Elevated aspartate aminotransferase	9 (38)	8 (25)	–	1 (3)
Elevated amylase	1 (3)	1 (3)	–	–
Elevated lipase	2 (6)	1 (3)	1 (3)	–
Hyponatremia	1 (3)	–	–	1 (3)
Peripheral neuropathy	2 (6)	2 (6)	–	–
Hypertension	2 (6)	–	2 (6)	–

Data are n (%), unless otherwise specified.

No patients had fatal treatment-related adverse events.