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. 2020 Feb 4;130(3):1417–1430. doi: 10.1172/JCI128678

Figure 6. Increased KLF4 levels in vitro and in vivo upon EGFR inhibition.

Figure 6

(A) Representative images of KLF4 expression (green) in PHKs after erlotinib or control DMSO exposure for 24 hours. Nuclei were stained with DAPI. Scale bars: 10 μm. Data are representative of 3 independent experiments. (B and C) Immunofluorescent staining with mouse anti-KLF4 (green) and rabbit anti–IL-36γ (red) antibodies of formalin-fixed, paraffin-embedded skin sections of acneiform eruption patients and healthy controls (HC). Nuclei were stained with DAPI. The white-boxed regions in B were zoomed separately in C. Scale bars: 50 μm (B) and 10 μm (C). Pictures are representative of 5 patients and 3 healthy individuals.