Figure 12. Treatment with r.TGF-β1 protein disrupts tumor vessel normalization and perfusion in Zeb1^iΔEC mice.

(A and B) Immunofluorescent images (A) and comparisons (B) of BV density, desmin⁺ pericyte and collagen type IV⁺ BM coverages along BVs, claudin 5 distribution on BVs, and lectin perfusion of BVs in LLC tumors dissected from the indicated mice (5 mice each). All data are represented as mean ± SD. **P < 0.01. Differences were tested using 1-way ANOVA with Tukey’s post hoc test.