Figure 7. Endothelial ZEB1 deletion enhances presence of tumor-infiltrating immune cells.

(A–E) Flow cytometric quantification of presence of CD8⁺ T cells (A), CD4⁺ T cells (B), CD4⁺Foxp3⁺ Tregs (C), tumor-associated dendritic cells (TADCs) (D), and tumor-associated B cells (TABCs) (E) in LLC tumors of Zeb1^WT and Zeb1^iΔEC mice (5 mice each). (F and G) Immunohistochemical images (F) and quantification (G) of CD8⁺ T cells in the peripheral and central regions of LLC tumors grown in Zeb1^WT and Zeb1^iΔEC mice (5 mice each). Magnified areas of dashed boxed sections are shown in right panels. All data are represented as mean ± SD. **P < 0.01. Differences were tested using unpaired 2-sided Student’s t test (A–E and G).