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. 2020 Jun 3;6(23):eaaz0742. doi: 10.1126/sciadv.aaz0742

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Copyright © 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).

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Fig. 3 — (A) Lineage tracing of Meis1^CreERT2-labeled cells by tamoxifen (TM) injection at different stages (TM.E8.5, n = 11; TM.E10.5, n = 3). (B) Lineage tracing of Hoxa13^CreERT2-labeled cells by tamoxifen injection at different stages (TM.E9.5, n = 7; TM.E10.5, n = 4; TM.E11, n = 4). (C and D) Schemes showing the boundaries of the regions colonized by Meis-expressing cells (C) and Hoxa13-expressing cells (D) at different labeling time points. Besides minor leakiness observed following injections at E9.5 (C), the lineage of Hoxa13-expressing cells respects the zeugopod-autopod boundary.