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. 2020 May 1;10(5):1548–1567.

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SLC25A18 attenuates CRC aerobic glycolysis in the xenograft tumor model. A. Representative photographs show subcutaneous tumor formation after implantation of HCT116 transduced with lenti-vector or lenti-oeSLC25A18. B, C. Tumor volume and tumor weight decreased significantly in the lenti-oeSLC25A18 group. D. Positive area of SLC25A18 IHC staining was evaluated. E. RT-PCR assay confirmed the SLC25A18 expression in mRNA level. F. Western blotting assay confirmed the protein level expression of SLC25A18 as well as CTNNB1, MYC, PKM2, LDHA related to aerobic glycolysis. ***, P < 0.001; ****, P < 1 × 10^-4.