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Summary of major type of immune cell changes at the premalignant and malignant stages
| Cell type | Premalignant | Malignant |
|---|---|---|
| T lymphocytes | ||
| CD4 | ↑ | ↑ |
| CD8 | ↑ | ↓ |
| Macrophages | ||
| M1 | ↑ | ↓ |
| M2 | ↑ | ↑ |
| DCs | ||
| iDC | ↑ | ↑↑ |
| mDC | ↑ | ↓↓ |
| Tregs | ↑ | ↑ |
| MDSC | ↑ | ↑ |
| NK cells | ||
| iNKT | ↑ | ↑↑ |
| NKT | ↑ | ↓↓ |
