Table 4.
Linear regression of GWG and maternal characteristics among HIV-infected women with live singleton births, subset cohort (n= 471)
| Unadjusted Models | Adjusted Models | |||
|---|---|---|---|---|
| Coefficient (95% CI) | p-value | Coefficient (95% CI) | p-value | |
| Age (years) | −0.008 (−0.014, −0.002) | 0.006 | −0.007 (−0.016, 0.003) | 0.156 |
| Height (cm) | −0.001 (−0.006, 0.004) | 0.710 | −0.003 (−0.008, 0.002) | 0.221 |
| BMI (kg/m2) | −0.016 (−0.025, −0.007) | 0.001 | −0.014 (−0.026, −0.001) | 0.030 |
| Hb (g/dL) | 0.005 (−0.028, 0.038) | 0.765 | 0.029 (−0.016, 0.073) | 0.203 |
| Blood pressure (mmHg) | ||||
| Normotensive | 1.000 | 1.000 | ||
| Hypertensive | −0.178 (−0.352, −0.003) | 0.046 | 0.082 (−0.134, 0.298) | 0.457 |
| ART status | ||||
| ART-initiation during pregnancy | 1.000 | 1.000 | ||
| ART-initiation before pregnancy | −0.017 (−0.087, 0.052) | 0.626 | −0.054 (−0.156, 0.049) | 0.304 |
| Marital status | ||||
| Single | 1.000 | 1.000 | ||
| Married | −0.039 (−0.111, 0.034) | 0.293 | 0.037 (−0.052, 0.125) | 0.414 |
| Education (Grade) | ||||
| Not completed high school | 1.000 | 1.000 | ||
| Completed high school | −0.001 (−0.082, 0.079) | 0.978 | −0.046 (−0.145, 0.053) | 0.361 |
| Socioeconomic status | ||||
| Medium SES | 1.000 | 1.000 | ||
| Low SES | 0.046 (−0.037, 0.130) | 0.275 | 0.076 (−0.009, 0.161) | 0.080 |
| High SES | −0.013 (−0.103, 0.077) | 0.777 | −0.043 (−0.141, 0.056) | 0.392 |
| Alcohol use | ||||
| No alcohol use | 1.000 | 1.000 | ||
| Alcohol use | −0.013 (−0.088, 0.063) | 0.742 | 0.020 (−0.079, 0.120) | 0.689 |
| GA at first ANC visit (weeks) | 0.003 (−0.003, 0.009) | 0.350 | 0.002 (−0.006, 0.010) | 0.567 |
| Parity (number) | −0.002 (−0.005, 0.001) | 0.196 | −0.020 (−0.095, 0.055) | 0.600 |
| Gravidity (number) | −0.023 (−0.055, 0.009) | 0.159 | −0.007 (−0.069, 0.084) | 0.852 |
| CD4 cell count (cells/μl) | 0.001 (−0.001, 0.002) | 0.567 | 0.001 (−0.001, 0.002) | 0.691 |
Hb - haemoglobin, SES - Socioeconomic status, GA - gestational age, ANC - antenatal care
All adjusted models include variables significantly different at baseline and on univariate analysis: maternal age, BMI, haemoglobin, parity and CD4 cell count. Missing data, n (%): Height n=2 (0.004), BMI and Marital status n=3 (0.01), Hb n=109 (0.2), Blood pressure n=13 (0.03), Education n=1 (0.002) SES n=11 (0.02), Alcohol use, Parity and Gravidity n=5 (0.01), GA at first ANC n=14 (0.03) CD4 count n=94 (0.2). Where data are missing on predictors, cases were excluded on the regression.