Table 5.
Association between adverse birth outcomes and GWG among HIV-infected women with live singleton births in the subset cohort
| Unadjusted Models | Adjusted Models | ||||
|---|---|---|---|---|---|
| N (%) N = 471 |
OR (95% CI) | p-value | aOR (95% CI) | p-value | |
| Delivery GA (weeks) | |||||
| Term (≥37) | 416 (88.3) | 1.00 | 1.00 | ||
| Spontaneous PTD (>37) | 19 (4.0) | 1.37 (0.11, 17.13) | 0.808 | 4.35 (1.55, 12.21) | 0.005 |
| Provider-initiated PTD (>37) | 33 (7.0) | 0.92 (0.36, 2.39) | 0.869 | 0.70 (0.14, 3.55) | 0.670 |
| Birth weight (g) | |||||
| Normal (2500–4000) | 374 (79.4) | 1.00 | 1.00 | ||
| Low (<2500) | 69 (14.7) | 1.38 (0.53, 3.58) | 0.506 | 1.90 (0.70, 5.15) | 0.209 |
| High (>4000) | 19 (4.0) | 3.19 (1.29, 7.91) | 0.012 | 3.00 (1.22, 7.34) | 0.016 |
| Size for GA (centile) | |||||
| Appropriate (10–90th) | 352 (74.7) | 1.00 | 1.00 | ||
| Small (<10th) | 78 (16.6) | 1.14 (0.58, 2.24) | 0.708 | 1.15 (0.55, 2.41) | 0.706 |
| Large (>90th) | 35 (7.4) | 2.19 (0.99, 4.87) | 0.054 | 2.03 (0.87, 4.73) | 0.100 |
OR - odds ratio, GA - gestational age, PTD - preterm delivery
Preterm model adjusted for maternal age, ART status, haemoglobin, parity, previous PTD
Birth weight, size for GA and birth outcome models adjusted for maternal age, ART status, haemoglobin and parity. Missing data, n (%): GA at delivery n=3 (0.6), Birthweight n=9 (1.9), Size for GA n=6 (1.3). Where data are missing on outcomes, cases were excluded on the regression. Interpretation of OR’s: Increase in GWG increases (OR>1) or decreases (OR<1) the likelihood of having spontaneous PTD/PI-PTD/LBW/HBW/SGA/LGA compared to respective reference categories.