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. Author manuscript; available in PMC: 2021 May 1.
Published in final edited form as: Diabetes Res Clin Pract. 2020 Apr 6;163:108139. doi: 10.1016/j.diabres.2020.108139

Figure 2.

Figure 2.

Receiver operating characteristic curves for gestational diabetes risk prediction models within the model testing subset (n=33,251).

AUC, area under the receiver operating characteristic curve; PAPP-A, pregnancy-associated plasma protein A; uE3, unconjugated estriol; INH, dimeric inhibin A. Maternal characteristics only model includes the following variables: race/ethnicity, age at delivery (natural cubic spline transformed), pre-pregnancy body mass index (BMI) (natural cubic spline transformed), family history of diabetes, and pre-existing hypertension.Maternal characteristics plus first trimester biomarker model includes the following variables: race/ethnicity, age at delivery (natural cubic spline transformed), prepregnancy BMI (natural cubic spline transformed), family history of diabetes, pre-existing hypertension, and first trimester PAPP-A multiple of the median (MoM) (natural log-transformed). Maternal characteristics plus first and second trimester biomarkers model includes the following variables: a: race/ethnicity, age at delivery (natural cubic spline transformed), pre-pregnancy BMI (natural cubic spline transformed), family history of diabetes, pre-existing hypertension, first trimester PAPP-A MoM (natural log-transformed), second trimester uE3 MoM (natural log-transformed), and second trimester INH MoM (natural log-transformed).