Table 4:

Diagnostic utility of testing in predicting STC alone

Finding	SN (%)	SP (%)	(+) LR	(−) LR
Imaging
Scintigraphy: generalized vs. left sided delay* 56	53.7	53.3	1.2	0.9
Rectal gas area <5cm2 on CT abd/pelvis scout film59	88.2	23.7	1.2	0.5
High stool burden on AXR via Leech method60	79.3	55.2	1.8	0.4
Physiology Testing
BET inability to expel (Total STC vs. NTC)32	80.0	33.3	1.2	0.6
Rectal hyposensitivity vs. normal sensation$21	80.0	36.4	1.3	0.5
Normal sensation vs. rectal hyposensitivity$21	20.0	63.6	0.6	1.3
Wireless motility capsule vs. ROM^	insufficient evaluation to predict STC
Total STC vs. NTC61–63	85.7 (82.7–86.3)	66.7 (54.8–78.7)	2.6 (2.1–5.6)	0.2 (0.2–0.3)

Data presented as medians (Q1,Q3)

Reference numbers in brackets are found in the Supplemental reference list.

^*Generalized STC: GC48 <3.6, Left sided delay: GC48 >3.8 + normal defecography

^$Rectal hyposensitivity is defined as elevation of >1 of three rectal sensory threshold volumes beyond normal range during simple balloon distension. Thresholds for men: first sensation volume >160mL, desire to defecate volume >230mL, or max tolerated volume >315 mL in men. Thresholds for women: first sensation >120mL, desire to defecate >210mL, max tolerated volume >325mL.

^{^}Wireless motility capsule colon transit time >59h vs. abnormal ROM (various methods) as the gold standard

Grey = SN/SP ≥85% with IQR <20%; (+)LR ≥2 with IQR <1.0, (−) LR ≤0.5 with IQR <0.5

Black = SN/SP ≥95% with IQR <20%, (+) LR ≥5 with IQR <1.0, (−) LR ≤0.2 with IQR <0.5