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Effect of VSL#3 supplementation on pro-inflammatory cytokines in brains of C57BL/6 (WT) and AppNL-G-F mice. Protein levels of (a) interleukin-1β (IL-1β), (b) IL-6, (c) tumor necrosis factor (TNF-α), and (d) lipocalin (LCN-2) from temporal cortices were examined by enzyme-linked immunosorbent assay (ELISA). (n=7 and outlier removal resulted in statistical analysis from n=6-7). Data are represented as mean ± S.E.M. Significant differences were determined by two-way ANOVA, * p<0.05.
