. Author manuscript; available in PMC: 2021 Jun 1.

Published in final edited form as: Mol Diagn Ther. 2020 Jun;24(3):279–298. doi: 10.1007/s40291-020-00464-9

Table 3.

Reproducible miRNAs Tested Through Different Detection Methods

Disease	Brain areas	Sample size	Methods	miRNA expression changes		Reference
Disease	Brain areas	Sample size	Methods	Up-regulation	Down-regulation	Reference
SZ	BA9	13 SZ, 2 Schizoaffective, and 21 Controls	Microarray and qPCR validation		miR-26b, miR-30b, miR-92, miR-24, and miR-30e	Perkins et al., 2007 [55]
	BA9	15 SZ and 15 Controls	Microarray and qPCR validation	let-7d, miR-128a, miR-16, miR-181b, miR-181a, miR-20a, miR-219, miR-27a, miR-29c, miR-7		Beveridge et al., 2010 [58]
	BA46	37 SCZ/schizoaffectives and 37 Controls	Microarray and qPCR validation	miR-17, miR-107, miR-134, miR-328, miR-382, miR-652		Santarelli et al., 2011 [61]
	STG	15 SZ and 15 Controls	Microarray and qPCR validation	miR-107, miR-15a, miR-15b, miR-16, miR-195, miR-181b, let-7e, miR-20a, miR-26b, miR-19a		Beveridge et al., 2010 [58]
	STG	21 SZ and 21 Controls	Microarray and qPCR validation	miR-181b		Beveridge et al., 2008 [56]
BD	BA9	8 SZ, 9 BD, and 13 Controls	Microarray and qPCR validation	miR-29c		Banigan et al., 2013 [52]

BA: Brodmann Area, BD: Bipolar Disorder, miRNA: microRNA, SZ: Schizophrenia, STG: Superior Temporal Gyrus