Table 5.

The Common Changes in miRNA Expression between Brain and Peripheral Tissues

Diagnosis	miRNA		Brain region	Blood source	Reference
	Up-regulation	Down-regulation			Brain	Blood
MDD	miR-330–3p		LC	Whole blood	Roy et al., 2017 [21]	Maffioletti et al., 2016 [11]
BD	miR-29c		BA9	Whole blood	Banigan et al., 2013 [51]	Maffioletti et al., 2016 [11]
SZ	miR-181b		BA9	Plasma	Beveridge et al., 2010 [57]	Sun et al., 2015 [84]
			STG		Beveridge et al., 2008 [55], Beveridge et al., 2010 [57]
	miR-34a		Amygdala	Plasma	Liu et al., 2018 [20]	Sun et al., 2015 [84]
			BA46		Kim et al., 2010 [58]
		miR-30e	BA9	PBMC	Perkins et al., 2007 [54]	Sun et al., [84]

BA: Brodmann Area, BD: Bipolar Disorder, LC: Locus Coeruleus, miRNA: microRNA, MDD: Major Depressive Disorder, PBMC: Peripheral Blood Mononuclear Cells, SZ: Schizophrenia, STG: Superior Temporal Gyrus