Table 1.
General characteristics and outcomes of patients. Data shown as mean (standard deviation), median [inter-quartile range], or n (%). Continuous data were compared using independent-sample t-test or Mann–Whitney U-test. Proportions were analysed using Fisher's exact test or χ2 test. HFNO, high-flow nasal oxygenation; SMO, standard mask oxygenation.
| Characteristic | Group HFNO | Group SMO | P-value |
|---|---|---|---|
| Patients, n | 28 | 30 | |
| Sex, M/F | 14/14 | 19/11 | |
| Age (yr) | 64.3 (11.6) | 67.1 (9.9) | |
| Weight (kg) | 66.9 (9.4) | 70.3 (9.1) | |
| Height (cm) | 165.5 (8.7) | 167.0 (7.8) | |
| Ventilatory frequency | 26.8 (5.9) | 27.7 (5.3) | |
| Co-morbidities, n (%) | |||
| Hypertension | 16 (57.1) | 19 (63.3) | |
| Diabetes mellitus | 3 (10.7) | 2 (6.7) | |
| Cardiovascular disease | 8 (28.6) | 10 (33.3) | |
| Primary and secondary outcomes | |||
| Pao2/Fio2 before intubation | 139.5 [118.3; 162.3] | 128.5 [121.5; 136.3] | 0.225 |
| Total time to intubation (s) | 68.5 [62.2; 74.0] | 76.0 [68.0; 90.5] | 0.005 |
| Lowest Spo2 during intubation | 94.0 [92.1; 95.8] | 91.2 [86.3; 93.0] | 0.001 |
| Mask ventilation for Spo2 <90%, n (%) | 1 (3.6) | 8 (26.7) | 0.015 |
| Percentage of minimum Spo2 >95% during intubation, n (%) | 8 (28.6) | 3 (10) | 0.071 |
| Percentage of Spo2 <80% during intubation, n (%) | 0 (0) | 2 (6.7) | 0.164 |