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. 2019 Dec 5;55(6):1029–1040. doi: 10.1038/s41409-019-0766-z

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — a Schematic representation of the experimental design. b Tracing of GFP⁺ and tdTomato⁺ cells by two-photon fluorescence microscopy at different time points after transplantation in the bone marrow cavity. c Quantification of the number of GFP⁺ and tdTomato⁺ cells per field in the injected tibias at multiple time points after transplantation. d Western blot of intracellular and extracellular PDGFB protein levels in GFP-MSCs, PDGFB-MSCs, and PDGFB-tdTomato-MSCs. e GO enrichment analysis of upregulated genes in PDGFB-tdTomato-MSCs harvested 1 week after transplantation (p < 0.05). SHG, Second harmonic generation. *p < 0.05.