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. 2020 Jun 4;96:636–647. doi: 10.1016/j.ijid.2020.05.113

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© 2020 The Author(s)

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Estimated effective reproduction number R_t for mainland China in (A) and for Hubei province in (B). The timing of strategies implemented are as follows: (C1) Huanan Seafood Wholesale Market closed on January 1, 2020; (C2) Detection kits for COVID-19 first used on January 16, 2020; (C3) The Chinese government amended the Law on the Prevention and Treatment of Infectious Diseases to include COVID-19 as a class-B infection but manage it as a class-A infection due to its severity on January 20, 2020; (C4) Lock-down strategy in Wuhan implemented on January 23, 2020; (C5) Spring festival holiday extended and self-quarantine measures kept on January 26, 2020.