Figure 2.

Increased expression of p-cav-1 in the spinal cord after diabetic neuropathic pain. (A) The western blot assay revealed that p-cav-1 expression increased in the spinal cord at 17, 21 and 28 days after STZ injection, when compared to the C group and PL group. (B) The quantification of western blot data obtained from (A). All data were presented as mean ± standard error of the mean (SEM); n=4. *P<0.05, **P<0.01, and ***P<0.001. (C) The immunofluorescence staining revealed that the major cav-1 (green) co-localized in the microglia (OX42, red). Scale bar =50 μm.