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Phosphorylated caveolin-1 may increase the ROS production through NOX2/Rac1 activation. (A-C) The western blot assay reveals that the p-caveolin-1, NOX2 and Rac1 expression changed in each group at 17 days (A), 21 days (B), and 28 days (C) after STZ injection. (D-F) The quantification of western blot data from [A-C] is shown. All data were presented as mean ± standard error of the mean (SEM), n=4. *P<0.05, **P<0.01, ***P<0.001.
