Figure 1.

SP miRNA levels are altered in benign prostate hyperplasia and malignant prostate tumor. Expression profiling of the eight miRNAs ((A) miR-107, (B) miR-142-3p, (C) miR-142-5p, (D) miR-223-3p, (E) miR-30a-5p, (F) miR-30d-5p, (G) miR-342-3p, (H) miR-93-5p) in total seminal fluid of healthy controls-non vasectomized (HCt-noV), vasectomized healthy controls (HCt-V), benign prostate hyperplasia-non vasectomized (BPH-noV), prostate cancer-non vasectomized (PCa-noV) and prostate cancer from men successfully vasectomized (PCa-V) obtained by RT-qPCR amplification. Data are shown as RQ values, which were calculated using the 2^dCp strategy and relative to the expression values of miR-30e-3p. The horizontal bar displays the median cellular expression level. Significant differences between groups are indicated: *P<0.05; **P<0.01 (Mann Whitney U test).