Table 3.

Performance of markers to distinguish BPH vs PCa

Markers	AUC (p-value)	IC 95%	Sensitivity %	Specificity %	PPV %	NPV %
PSA	0.704 (0.157)	0.496-0.913	100	0	82.8	0
miR-107	0.708 (0.149)	0.522-0.894	100	0	82.8	0
miR-142-3p	0.633 (0.356)	0.292-0.975	95.8	0	81.5	0
miR-142-5p	0.638 (0.341)	0.349-0.926	100	20	85.7	100
miR-223-3p	0.617 (0.419)	0.314-0.919	100	0	82.8	0
miR-30a-5p	0.683 (0.204)	0.409-0.957	100	20	85.7	100
miR-30d-5p	0.592 (0.525)	0.332-0.851	100	0	82.8	0
miR-342-3p	0.638 (0.341)	0.413-0.862	100	0	82.8	0
miR-93-5p	0.338 (0.260)	0.143-0.532	100	0	82.8	0
Combined miRNA-model (142-3p+223-3p+93-5p)	0.783 (0.05)	0.570-0.997	100	40	88.9	100
Combined PSA_miRNA-model (PSA+142-3p+223-3p+93-5p)	0.858 (0.013)	0.636-1.081	100	60	92.3	100

Statistically significant AUC values (p≤0.05) are depicted in bold.