Table 5.

Correlation of SOCS family members with tumor grades of OC patients

Gene	Grades	Case-low1	Case-high2	HR (95% CI)	p-value
SOCS1	I + II	206	174	0.62 (0.46-0.83)	0.0011**
	III	451	169	0.51 (0.35-0.76)	0.00064**
	IV	12	8	0.58 (0.21-1.55)	0.27
SOCS2	I + II	139	64	0.77 (0.5-1.18)	0.23
	III	136	68	1.28 (0.76-2.16)	0.34
	IV	3	15	1219678945.7(0-lnf)	0.0043*
SOCS3	I + II	81	122	1.72 (1.1-2.68)	0.016*
	III	128	76	0.66 (0.38-1.14)	0.13
	IV	10	8	0.42 (0.14-1.26)	0.11
SOCS4	I + II	110	93	0.78 (0.52-1.18)	0.24
	III	53	151	0.48 (0.28-0.82)	0.0055*
	IV	4	14	2.5 (0.68-9.21)	0.16
SOCS5	I + II	202	178	1.79 (1.34-2.4)	6.3e-05**
	III	389	231	1.52 (1.13-2.03)	0.0047*
	IV	14	6	3.45 (1.08-10.97)	0.026*
SOCS6	I + II	131	72	0.61 (0.38-0.96)	0.032*
	III	105	99	0.58 (0.34-0.98)	0.038*
	IV	13	5	0.53 (0.15-1.88)	0.32
SOCS7	I + II	62	141	1.45 (0.91-2.33)	0.12
	III	147	57	1.59 (0.95-2.67)	0.076
	IV	12	6	1.87 (0.65-5.38)	0.24
CIS	I + II	118	85	0.65 (0.43-0.99)	0.043*
	III	91	71	0.7 (0.45-1.1)	0.12
	IV	11	7	0.4 (0.13-1.28)	0.11

¹Cases-low: patient number-low expression of the corresponding gene.

²Cases-high: patient number-high expression of the corresponding gene.

^*P < 0.05;

^**P < 0.01.