Table 6.
Correlation of SOCS members with OC patients receiving different chemotherapy regimes
Gene | Chemotherapy | Case-low1 | Case-high2 | HR (95% CI) | p-value |
---|---|---|---|---|---|
SOCS1 | contains platin | 505 | 904 | 0.84 (0.73-0.97) | 0.017* |
contains taxol | 318 | 475 | 0.71 (0.59-0.86) | 0.00037** | |
SOCS2 | contains platin | 262 | 216 | 1.3 (1.03-1.64) | 0.026* |
contains taxol | 198 | 159 | 1.24 (0.94-1.66) | 0.13 | |
SOCS3 | contains platin | 287 | 191 | 1.24 (0.98-1.57) | 0.07 |
contains taxol | 221 | 136 | 1.22 (0.91-1.63) | 0.19 | |
SOCS4 | contains platin | 260 | 218 | 0.89 (0.71-1.13) | 0.33 |
contains taxol | 198 | 159 | 0.82 (0.61-1.09) | 0.17 | |
SOCS5 | contains platin | 679 | 730 | 1.41 (1.22-1.62) | 1.8e-06** |
contains taxol | 416 | 377 | 1.48 (1.23-1.79) | 3.5e-05** | |
SOCS6 | contains platin | 125 | 353 | 1.15 (0.88-1.5) | 0.3 |
contains taxol | 239 | 118 | 0.79 (0.57-1.09) | 0.15 | |
SOCS7 | contains platin | 269 | 209 | 1.33 (1.05-1.67) | 0.016* |
contains taxol | 239 | 118 | 1.38 (1.03-1.85) | 0.03* | |
CIS | contains platin | 353 | 125 | 1.32 (1.03-1.69) | 0.03* |
contains taxol | 267 | 90 | 1.31 (0.96-1.79) | 0.091 |
Cases-low: patient number-low expression of the corresponding gene.
Cases-high: patient number-high expression of the corresponding gene.
P < 0.05;
P < 0.01.