Table 7.
Correlation of SOCS family members with debulk status of OC patients
Gene | Debulk | Case-low1 | Case-high2 | HR (95% CI) | p-value |
---|---|---|---|---|---|
SOCS1 | optimal | 245 | 556 | 0.85 (0.68-1.05) | 0.13 |
suboptimal | 213 | 323 | 0.8 (0.65-0.98) | 0.03* | |
SOCS2 | optimal | 60 | 183 | 1.34 (0.81-2.21) | 0.26 |
suboptimal | 117 | 118 | 1.52 (1.13-2.05) | 0.0055** | |
SOCS3 | optimal | 112 | 131 | 1.73 (1.13-2.64) | 0.01* |
suboptimal | 59 | 176 | 0.75 (0.54-1.05) | 0.096 | |
SOCS4 | optimal | 166 | 77 | 1.45 (0.95-2.21) | 0.082 |
suboptimal | 161 | 74 | 0.76 (0.55-1.06) | 0.11 | |
SOCS5 | optimal | 383 | 418 | 1.7 (1.38-2.09) | 3.7e-07** |
suboptimal | 307 | 229 | 1.28 (1.05-1.57) | 0.015* | |
SOCS6 | optimal | 172 | 71 | 0.4 (0.23-0.7) | 0.001** |
suboptimal | 174 | 61 | 1.41 (1.01-1.95) | 0.041* | |
SOCS7 | optimal | 170 | 73 | 1.17 (0.76-1.8) | 0.47 |
suboptimal | 170 | 65 | 1.58 (1.15-2.18) | 0.0045** | |
CIS | optimal | 158 | 85 | 0.62 (0.4-0.96) | 0.031* |
suboptimal | 116 | 119 | 1.38 (1.02-1.86) | 0.0371* |
Cases-low: patient number-low expression of the corresponding gene.
Cases-high: patient number-high expression of the corresponding gene.
P < 0.05;
P < 0.01.