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. 2020 May 15;12(5):1640–1657.

Figure 5.

Figure 5

Effects of PD-L1 or SREBP-1 knockdown on expression of E-cadherin, N-cadherin, and vimentin in GR cells with EMT. A, B. Western blot results showed that PD-L1 or SREBP-1 gene knockdown decreased expression of vimentin and N-cadherin and increased expression of E-cadherin. C, D. RT-PCR showed that expression of E-cadherin was increased. E, F. Immunofluorescent staining showed that expression of vimentin was decreased and expression of E-cadherin was increased. Data are represented as mean ± SEM (n=3). All experiments were repeated at least three times and representative data are shown. *P<0.05, **P<0.01, compared to control group. A, C, E. HCC827/GR/EMT cells; B, D, F. PC9/GR/EMT cells.