Figure 4.

Histopathological analysis of the tumor tissues with trichrome staining (A), CK19 (B) and Ki67 (C) immunostainings for assessment of treatment effects. The subjects treated with DC vaccine had significantly lower fibrosis (P<0.01) and higher CK19^* (P<0.01) area while there were no significant differences for Ki67^* (P > 0.05) cells. Besides, the subjects treated with dinaciclib had significantly higher CK19^* area (P=0.05) and lower number Ki67^* (P=0.03) cells while no significant difference was observed in fibrosis pepercentage (P > 0.05).