Table 3.
Target | Disease | Preclinical/clinical | Radiotracer |
---|---|---|---|
iNOS | Acute lung inflammation | Clinical | 18F-NOS [141,142] |
Heart transplantation | Clinical | 18F-NOS [143] | |
Fpr1 | Osteoarthritis | Preclinical | cFLFLF-PEG-64Cu [144] |
CRIg | Rheumatoid arthritis | Preclinical | 99mTc-NbV4m119 [146] |
CD80 | Atherosclerosis | Preclinical | 11C-AM7 [147,148] |
CD163 | Collagen-induced arthritis | Preclinical | 68Ga-ED2 [149] |
CD11b | Cancer | Preclinical | 64Cu-NOTA-αCD11b-mAb [150]; 89Zr-anti-CD11b Ab [151] |
Inflamed ear/IBD/Atherosclerosis | Preclinical | 64Cu-αCD11b [152]; 89Zr-α-CD11b [153]; 99mTc-anti-CD11b [154] | |
CD169 | Allograft rejection | Preclinical | 99mTc-SER-4 [155] |
CD68 | Atherosclerosis | Preclinical | 64Cu-CD68-Fc [157] |
F4/80 | Breast tumor | Preclinical | 111In-anti-F4/80-A3-1 [156] |