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. 2020 Jun 3;10:9024. doi: 10.1038/s41598-020-65920-2

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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hsa_circ_101237 knockdown hinders the proliferation, the migration and the invasion of NSCLC cells. (A) Hsa_circ_101237 level was detected by qRT-PCR in sh-con or sh-circ_101237 transfected cells. (B,C) Evaluation of the viability exhibited by cell was performed via the CCK-8 assay in cells transfected by sh-con or sh-circ_101237. (D) Colony Formation Assay helped determine the impact of hsa_circ_101237 on colony formation ability. (E) Transwell migration assay helped determine the migration of H1299 cells and A549 cells following the transfection. (F) Transwell invasion assay aimed at analyzing the invasion process of H1299 cells and A549 cells under the transfection of sh-con or sh-circ_101237. *P < 0.05; **P < 0.01; ***P < 0.001.