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. 2020 Jun 3;10:9024. doi: 10.1038/s41598-020-65920-2

Figure 5.

Figure 5

MAPK1 over-expression hinders the way that hsa_circ_101237 knockdown affects the biological behavior exhibited by NSCLC cells. (A) qRT-PCR assay together with Western blot assays helped determine the MAPK1 mRNA levels in A549 cells and H1299 cells under the transfection of sh-con, sh-circ_101237 alone or the pcDNA-MAPK1. (B,C) CCK-8 assay was conducted to measure the viability exhibited by A549 cells and H1299 cells at 24 h, 48 h, 72 h and 96 h following the transfection. (D,E) Transwell migration assay was performed to detect the migration and the invasion of cells in A549 cells and H1299 cells under the transfection of sh-con, sh-circ_101237 alone or the pcDNA-MAPK1. *P < 0.05; **P < 0.01; ***P < 0.001.