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. 2020 May 28;8:270. doi: 10.3389/fped.2020.00270

Table 3.

Suggested settings for CPAP, Bi-PAP, NIPPV, and HFNC.

Mode of NIV Initial settings Max settings Weaning parameters Lowest settings
NCPAP 5–6 cmH2O 8–10 cmH2O 1 cmH2O 4 cmH2O
Bi-PAP High Pressure 10 cmH2O
Low Pressure 5 cmH2O
Rate 20/min
High Pressure 15 cmH2O
Low Pressure 8 cmH2O
Rate 30/min
1 cmH2O
wean the rate by 2–4 /min every 6 h
High/Low Pressure 8/5 cm H2O
Rate 0
NIPPV PIP 20 cmH2O
PEEP 6 cmH2O Inspiratory time 0.5 s
Rate 40/min
PIP 35-38 cmH2O
PEEP 8–10 cmH2O
Rate 50/min
wean PIP first by 1–2 until lowest possible PIP
wean the rate by 2–4 /min every 6 h
PIP 12 or 15 cmH2O
PEEP 4–5 cmH2O
Rate 20/min
HFNC gas flow 4–6 L/min 8 L/min. 0.5–1.0 L/min 1–4 L/min

NIV, non-invasive ventilation; NCPAP, nasal continuous positive airway pressure; NIPPV, nasal intermittent positive pressure ventilation; HFNC, high flow nasal cannula; PIP, peak inspiratory pressure; PEEP, positive end expiratory pressure.