Table 4.

Interventions to improve rates of successful extubation in preterm infants.

Preventing extubation failures	Risk ratio [95% CI]	NNT [95% CI]
NCPAP vs. Head-Box	0.59 [0.48–0.72]	6 [3–9]
NCPAP vs. nHF	1.11 [0.84–1.47]	–
Methylxanthines	0.48 [0.32–0.71]	4 [2–7]
DOXAPRAM	0.80 [0.22–2.97]	–
NIPPV vs. NCPAP	0.70 [0.60–0.81]	8 [5–13]
NS-NIPPV or Bi-PAP vs. NCPAP	064 [0.44–0.95]	8 [4–50]
SNIPPV vs. NCPAP	0.25 [0.15–041]	4 [2–5]
NS-NIPPV or sNIPPV vs. NCPAP	0.28 [0.18–043]	4 [2–5]

NS-NIPPV, non-synchronized NIPPV; sNIPPV, synchronized NIPPV; nHF, High flow nasal cannula. Ferguson et al. (75).