Table 6.
Studies comparing Noninvasive neutrally adjusted ventilator assist (NIV NAVA) to other forms of non-invasive ventilation.
| References | Type of study | Comparison | GA (n) | Reintubation | CO2 clearance | Syn | Complications | Oxygen requirement/IMV duration |
Outcome (Death/BPD) |
|---|---|---|---|---|---|---|---|---|---|
| Lee et al. (90) | Retrospective | NCPAP | <30 (30) | P = 0.04 | NS | – | – | NS | NS |
| Kallio et al. (91) | Prospective | NCPAP | 28–36 (40) | NS | NS | NS | NS | NS | NS |
| Yonehara et al. (92) | Retrospective | NIPPV | <30 (34) |
NS | – | – | NS | – | – |
| Lee et al. (93) | Observational crossover | NIV-PS | <32 (15) |
– | – | P <0.001 | – | – | – |
| Gibu et al. (16) | Observational crossover | NIMV | <37 (11) | – | NS | P < 0.01 | P < 0.01 | P < 0.01 | – |
| Yagui et al. (94) | Randomized controlled | NCPAP | Preterm <1,500 g (123) |
NS | – | – | NS | P < 0.01 | NS |
| Yagui et al. (95) | Retrospective | NCPAP | ELBW | P = 0.02 | – | – | NS | P = 0.02 | NS |
NIPPV, Nasal intermittent positive pressure ventilation; NCPAP, Nasal continuous positive pressure ventilation; NIV-PS, Non-invasive ventilation-Pressure support; GA, Gestational age.
IMV: invasive mechanical ventilation; Syn-synchronization.