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Effect of nitrate and L-NAME on insulin release (a) and content (b) in experimental groups: Data are expressed as means + SEM of three independent replicates. n = 10 batches of eight islets incubated for 60 min in 1 ml RPMI-1640 media supplemented with 5 mmol/l glucose. Differences were analyzed by One way ANOVA (post Hoc:Tukey)
*P < 0.05, **P < 0.01, ***P < 0.001 vs. Control (c) group.
# P < 0.05 vs Diabetic (D) group.
