Table 2.
Biochemical parameters in control and T2DM subjects
| Biochemical parameter | Control (n = 50) mean ± SEM |
T2DM group (n = 50) mean ± SEM |
p value |
|---|---|---|---|
| Plasma glucose (mg/dL) | 100.9 ± 1.02 | 195.8 ± 13.19 | < 0.001 |
| HbA1c (%) | 5.2 ± 0.04 | 9.1 ± 0.29 | < 0.001 |
| MDA (µmol) | 0.29 ± 0.02 | 2.0 ± 0.10 | < 0.001 |
| SOD (U/ml) | 18.3 ± 1.43 | 14.4 ± 1.25 | < 0.05 |
| Catalase (KU) | 147.4 ± 11.28 | 105.6 ± 9.00 | < 0.01 |
| GSH (µMol) | 117.7 ± 2.05 | 71.9 ± 1.62 | < 0.001 |
| MGO (nmol) | 121.1 ± 6.52 | 221.1 ± 9.50 | < 0.001 |
| sRAGE (ng/ml) | 7.7 ± 0.86 | 5.3 ± 0.64 | < 0.05 |
Data are expressed as mean ± SEM. Data of patient group compared with control group. P < 0.05 considered as statistical significant difference. HbA1c-glycated hemoglobin; MDA- malondialdehyde; SOD-superoxide dismutase; GSH- reduced glutathione; MGO-methylglyoxal; sRAGE; soluble form of receptor for advanced glycation end product