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. 2020 May 28;11:366. doi: 10.3389/fneur.2020.00366

Table 6.

Meta-analysis results: SWI mean values of PD and HC were used to calculate the effect size value and confidence interval.

References SN division Method PD HC Hedge's g SE Confidence interval
N Mean SD N Mean SD Low High
Gupta et al. (45) Global SWI hypointensity 11 0.36 0.81 11 0.64 0.67 0.36 0.43 −0.48 1.21
Zhang et al. (49) Ipsilateral Phase values 40 0.13 0.05 26 0.12 0.04 0.21 0.25 −0.28 0.71
Contralateral*** 0.16 0.05 0.12 0.04 0.85 0.26 0.34 1.37
Jin et al. (50) Global*** Phase values 87 −0.18 0.03 50 −0.16 0.03 0.66 0.18 0.31 1.02
Lotfipour et al. (51) SN Relative susceptibility 9 0.05 0.01 11 0.04 0.01 0.96 0.48 0.02 1.89
SNc* 0.06 0.01 0.04 0.01 1.92 0.55 0.84 2.99
Wang et al. (46) Global* Phase values 16 −0.23 0.05 44 −0.17 0.07 0.91 0.30 0.31 1.50
Rossi et al. (23) Lateral SNc SWI contrast 36 7.20 3.50 21 9.10 5.20 0.45 0.28 −0.10 0.99
Medial SNc* 5.70 5.90 9.90 6.50 0.68 0.28 0.12 1.23
Wang et al. (47) SNc** Phase values 20 0.03 0.03 14 0.08 0.02 1.85 0.42 1.03 2.67
SNr** −0.55 0.18 −0.37 0.17 1.00 0.37 0.27 1.72
Wu et al. (48) Global* Phase values 54 −0.13 0.01 40 −0.10 0.02 1.97 0.25 1.48 2.47
Isaias et al. (12) Ipsilateral Phase values 18 0.16 0.05 18 0.13 0.03 0.71 0.34 0.04 1.39
Contralateral 0.15 0.05 0.13 0.03 0.47 0.34 −0.19 1.14
Martin-Bastida et al. (52) Global** Phase values 70 0.11 0.02 20 0.04 0.02 3.47 0.36 2.76 4.18

All SN subdivisions were included.

***

Significantly different from controls (p < 0.001).

**

Significantly different from controls (p < 0.01).

*

Significantly different from controls (p < 0.05).