Fig. 5.

Sodium nitrate preconditioning reduces thermal algesia alterations in diabetic rats. a Changes of tail withdrawal latency among groups at 0th, 7th, 30th, and 60th days. b Changes of hot plate latency among groups at 0th, 8th, 31th, and 61th days. Data represent mean ± SEM of 8 rats per group. One-way ANOVA followed by Tukey test was used for multiple comparisons. **p < 0.01, ***p < 0.001 versus control group; ^##p < 0.01, ^###p < 0.001 versus D group; ⁺p < 0.05 versus diabetic received insulin group. Comparisons between the different times in each group were performed by Repeated measures one-way ANOVA and Bonferroni post-test. !p < 0.05 and !!p < 0.01